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Glossary  /  Drug Development  /  Mechanism of Action (MoA)

Mechanism of Action (MoA)

The mechanism of action (MoA) describes how a drug produces its effects at the molecular, cellular, or tissue level.

Understanding the MoA is crucial for predicting the therapeutic and side effects of a drug. This knowledge helps in optimizing drug dosages and identifying potential drug interactions.

Additionally, elucidating the MoA can aid in the development of combination therapies that target multiple pathways, enhancing treatment efficacy.Advances in computational biology and high-throughput screening have significantly improved our ability to uncover the MoA of new and existing drugs.

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